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Tetanus vaccine affect an adults brain

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Purpose: Warfarin is commonly used among patients who receive influenza, pneumococcal, and tetanus and diphtheria toxoid vaccines, and persons on warfarin therapy may also receive Hepatitis A vaccine. There has been concern that vaccinations could potentially alter coagulation parameters in patients on warfarin therapy. We sought to determine whether vaccinations are associated with changes in International Normalized Ratio INR in persons on long-term warfarin therapy. Methods: We conducted a retrospective cohort study of members of Group Health, a health maintenance organization HMO in western Washington State, who were aged 18 years and older and who were on stable long-term warfarin therapy between 1 January and 31 December We made within-person comparisons between mean INR values in the 28 days after receipt of influenza, pneumococcal, tetanus, or hepatitis A vaccine versus mean INR values during other times. Results: Receipt of influenza vaccine was not associated with a change in INR value mean change, 0.
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Vaccines, Autism and Brain Damage: What's in a Name?

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Disease factsheet about tetanus

Researchers from Johns Hopkins University determined that immune responses to the tetanus vaccine were not changed when rituximab in combination with methotrexate MTX was compared with MTX alone in patients with rheumatoid arthritis RA. RA patients may be at an increased risk of infection because of impaired immune function due to the disease as well as from the use of immunsuppressive medications. As a result, vaccinations against infections are an essential part of rheumatic disease management. How immunosuppressive agents alter the effectiveness of vaccines in RA patients was the focus of the clinical trial led by Clifton O.
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Tetanus-Diphtheria Toxoids, Adult Side Effects

Vaccines have saved untold millions of lives, and the vast majority of people who get them suffer no major problems. But there's a trade-off: occasionally, vaccines cause injury or death. Very rarely, patients are left with what's known as "encephalopathy", the medical term for brain damage. In fact, CBS News has found nearly 1, cases in which vaccine-related brain damage has been compensated in court over the past 20 years. The debate over any links between vaccines and autism - a behavior problem triggered by brain damage - couldn't be more contentious.
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Tetanus is a serious but preventable bacterial infection that affects the nerves. Commonly referred to as lockjaw , the disease is spread by contact with an object or surface that has been contaminated with Clostridium tetani. Tetanus can be prevented with a simple vaccine. However, if you have not been vaccinated and are infected, the disease can cause muscle spasms ranging from mild to life-threatening. There are currently no blood tests available to diagnose tetanus.
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