Acute overdosage with doxorubicin enhances the toxic effects of mucositis, leukopenia and thrombocytopenia. Treatment of acute overdosage consists of treatment of the severely myelosuppressed patient with hospitalization, antimicrobials, platelet transfusions and symptomatic treatment of mucositis. The mg doxorubicin hydrochloride injection vial is packaged as a multiple dose vial and caution should be exercised to prevent inadvertent overdosage. Treatment consists of vigorous management of congestive heart failure with digitalis preparations, diuretics, and after-load reducers such as ACE inhibitors.
BluIRIS Powder-Free Nitrile Medical Examination Gloves - Medium
Doxorubicin is a prescription medication used to treat certain types of cancer in adults and children including breast cancer, lung cancer , and ovarian cancer. Doxorubicin belongs to a group of drugs called anthracyclines, which slow and stop the growth of cancer cells. This medication comes in an injectable form and is given by injection into a vein intravenously by a healthcare provider. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Infusion site reactions. Serious infusion site reactions can happen with doxorubicin.
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If you are a consumer or patient please visit this version. Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. Doxorubicin consists of a naphthacenequinone nucleus linked through a glycosidic bond at ring atom 7 to an amino sugar, daunosamine. The anthracycline ring is lipophilic, but the saturated end of the ring system contains abundant hydroxyl groups adjacent to the amino sugar, producing a hydrophilic center. The molecule is amphoteric, containing acidic functions in the ring phenolic groups and a basic function in the sugar amino group.
Metrics details. Medical gloves are an important piece of personal protective equipment that prevents exposure to antineoplastic agents. The permeability of medical gloves to antineoplastic agents is a crucial factor in the appropriate selection of gloves. However, the relationship between glove permeability and material type, thickness, and surface treatment is poorly understood. A continuous flow in-line cell device was used for the evaluation of the permeation of five antineoplastic agents etoposide, cyclophosphamide, doxorubicin hydrochloride, paclitaxel, and fluorouracil through medical gloves.